A tool to support the clinical decisions of doctors and health professionals, not for self-diagnosis or self-treatment.
This calculator is inside the patient's file in Clinicato: open it from "Medical tools" while you chart the visit, it fills in from the patient's details and vital signs where they are recorded, and adds its result to the visit's plan in one tap, with the "Medical tools" add-on. Try it in your clinic
Calculator
How it works and when to use it
PSA density = PSA ÷ prostate volume in mL, and the ultrasound volume = length × width × height × 0.52 (ellipsoid formula).
A density above 0.15 ng/mL/mL is linked to a higher chance of clinically significant prostate cancer (Benson et al.), and helps, with the examination and MRI, decide on a biopsy.
Reference: PSA density = PSA ÷ prostate volume; ellipsoid volume = L × W × H × 0.52; 0.15 ng/mL/mL threshold: Benson MC et al. J Urol 1992;147:815-6
Frequently asked questions
Why work out density and not just PSA?
Benign enlargement raises PSA, so its ratio to volume separates the rise expected from size from a more suspicious one.
Does the number alone decide a biopsy?
No, the decision rests on age, examination, family history, MRI and the PSA trend over time.
Tools you may also need
- Ideal and adjusted body weight (Devine) Ideal weight, actual weight as a percentage of it, and adjusted weight.
- Creatinine clearance calculator Creatinine clearance in mL/min with three weights.
- eGFR calculator eGFR in mL/min/1.73m² and its stage from G1 to G5.
- Pack-years calculator Pack-years, and whether they meet the lung cancer screening criterion.
- Corrected calcium calculator Corrected calcium in mg/dL and mmol/L.
- ASA physical status classification The ASA class, its definition and examples.
Clinic software for this specialty
Try Clinicato for your clinic
These calculators are free here for everyone, and in Clinicato 49 medical tools work inside the patient's file with the "Medical tools" add-on: filled from the visit and the vital signs, with the result added to the visit's plan, next to appointments, prescriptions and invoices.